Table 1.
All breast cancer at 75+ yrs | >7 mos to </= 2 yrs | >2 yrs to <5 yrs | >/= 5 yrs or no mammogram reported | ||||||
---|---|---|---|---|---|---|---|---|---|
N | % | N | % | N | % | N | % | ||
Breast cancer-grade | Well differentiated | 498 | 26.02 | 375 | 26.82 | 91 | 24.46 | 32 | 22.22 |
Moderately differentiated | 827 | 43.21 | 602 | 43.06 | 166 | 44.62 | 59 | 40.97 | |
Poorly differentiated/anaplastic | 451 | 23.56 | 318 | 22.75 | 92 | 24.73 | 41 | 28.47 | |
Unknown/not done | 138 | 7.21 | 103 | 7.37 | 23 | 6.18 | 12 | 8.33 | |
Summary Stage (SEER) | Localized | 1477 | 77.17 | 1078 | 77.11 | 292 | 78.49 | 107 | 74.31 |
Regional | 409 | 21.37 | 304 | 21.75 | 71 | 19.09 | 34 | 23.61 | |
Distant | 28 | 1.46 | 16 | 1.14 | 9 | 2.42 | 3 | 2.08 | |
Estrogen receptor positive | Yes | 1557 | 85.93 | 1152 | 86.88 | 299 | 84.94 | 106 | 79.10 |
No | 255 | 14.07 | 174 | 13.12 | 53 | 15.06 | 28 | 20.90 | |
Her2/Neu | Positive | 195 | 10.19 | 145 | 10.37 | 36 | 9.68 | 14 | 9.72 |
Negative or borderline | 1347 | 70.38 | 994 | 71.10 | 254 | 68.28 | 99 | 68.75 | |
Unknown/Not done | 372 | 19.44 | 259 | 18.53 | 82 | 22.04 | 31 | 21.53 | |
Diagnosis year | Before 2003 | 715 | 37.36 | 528 | 37.77 | 138 | 37.10 | 49 | 34.03 |
2003 and after | 1199 | 62.64 | 870 | 62.23 | 234 | 62.90 | 95 | 65.97 | |
Body-mass index (kg/m2), baseline | <25 | 640 | 33.65 | 487 | 35.04 | 109 | 29.46 | 44 | 30.99 |
25 – <30 | 687 | 36.12 | 506 | 36.40 | 138 | 37.30 | 43 | 30.28 | |
>=30 | 575 | 30.23 | 397 | 28.56 | 123 | 33.24 | 55 | 38.73 | |
Race/ethnicity | White | 1756 | 91.75 | 1278 | 91.42 | 343 | 92.20 | 135 | 93.75 |
All other | 158 | 8.25 | 120 | 8.58 | 29 | 7.80 | 9 | 6.25 | |
Education level | High school diploma/GED or less | 391 | 20.51 | 284 | 20.40 | 77 | 20.75 | 30 | 20.98 |
Some school after high school | 758 | 39.77 | 544 | 39.08 | 149 | 40.16 | 65 | 45.45 | |
College graduate or above | 757 | 39.72 | 564 | 40.52 | 145 | 39.08 | 48 | 33.57 | |
Charlson Comorbidity Index at baseline | 0 | 1196 | 64.47 | 874 | 64.45 | 230 | 63.71 | 92 | 66.67 |
1 | 423 | 22.80 | 310 | 22.86 | 84 | 23.27 | 29 | 21.01 | |
2 | 165 | 8.89 | 123 | 9.07 | 29 | 8.03 | 13 | 9.42 | |
3+ | 71 | 3.83 | 49 | 3.61 | 18 | 4.99 | 4 | 2.90 | |
Ever married | No | 88 | 4.61 | 69 | 4.95 | 9 | 2.43 | 10 | 6.94 |
Yes | 1820 | 95.39 | 1324 | 95.05 | 362 | 97.57 | 134 | 93.06 | |
Breast biopsy at baseline | No | 1278 | 70.45 | 919 | 69.41 | 257 | 71.99 | 102 | 76.69 |
Yes | 536 | 29.55 | 405 | 30.59 | 100 | 28.01 | 31 | 23.31 | |
Study participation | HT Randomized | 312 | 16.30 | 220 | 15.74 | 60 | 16.13 | 32 | 22.22 |
DM Randomized and not in HT | 438 | 22.88 | 304 | 21.75 | 103 | 27.69 | 31 | 21.53 | |
OS Enrolled | 1164 | 60.82 | 874 | 62.52 | 209 | 56.18 | 81 | 56.25 | |
Hormone trial assignment or use at baseline | Placebo/Non-user | 1068 | 55.89 | 740 | 53.01 | 222 | 59.84 | 106 | 73.61 |
Estrogen Alone | 456 | 23.86 | 350 | 25.07 | 84 | 22.64 | 22 | 15.28 | |
Estrogen + Progesterone | 387 | 20.25 | 306 | 21.92 | 65 | 17.52 | 16 | 11.11 |
HT - Hormone Trials
DM - Dietary Modification
OS – Observational Study