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Expression of cyclooxygenase 1 (COX1) protein by adult rat lungs stimulated in vitro with normal (HbAA) or sickle cell (HbSS) peptides. Adult rat lungs were prepared for studies as described in “Methods.” Proteins were prepared, and COX1 expression was measured by Western blotting. There was no significant difference in COX1 expression among the 3 groups of lung explants. “Krebs” denotes the Krebs buffer control. Data are means + SEM.
