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Cardiac fibrosis in diet-resistant/diet-induced obesity (DR/DIO) rats. Eight-week-old male DR and DIO rats were fed either a low- or a high-fat diet ad lib. for 5 months. Representative bright-field micrographs of picrosirius red–stained heart regions are shown: right ventricle (RV), septum, and left ventricle (LV). No differences were noted in collagen deposition due to diet or genetic background.
