TABLE 2.
Rates of positive results from the version 1.5 and 1.0 UltraSensitive Roche HIV-1 MONITOR tests in assays of coded samples of HIV-1 spiked into plasma when a result was considered positive if the OD for the undiluted PCR-amplified sample was ≥0.20 and the estimated RNA concentration was ≥50 copies/ml
| Nominal concn (copies/ml) | % Positive results (total assays)
|
P | |
|---|---|---|---|
| Version 1.0 | Version 1.5 | ||
| 0 | 0 (20) | 0 (20) | |
| 15 | 0 (30) | 3.3 (30) | >0.99b |
| 25 | 15.0 (80) | 22.5 (80) | 0.22a |
| 50 | 62.9 (70) | 78.6 (70) | 0.0411a |
| 100 | 100 (40) | 97.5 (40) | >0.99b |
a
Pearson chi-square.
b
Fisher's exact test.