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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Curr Eye Res. 2014 Feb 21;39(8):759–774. doi: 10.3109/02713683.2013.877936

Figure 3. Regulation of lymphangiogenic factor VEGF-c expression in macrophages via CD36-TSP interaction.

Figure 3

Binding of CD36 by thrombospondin inhibits TGF-β-induced VEGF-c expression in macrophages. In a normal cornea such regulation is likely with TSP-2:CD36 interactions that may prevent VEGF-c secretion in response to any TGF-b activated during normal wound healing processes.