Skip to main content
. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Curr Eye Res. 2014 Feb 21;39(8):759–774. doi: 10.3109/02713683.2013.877936

Figure 4. Abberations in wound healing of TSP-1 deficient cornea.

Figure 4

C57BL/6 mouse eyes 3 weeks (A, B) or 1-week (C, D) post-keratectomy in wild type (WT: A, C) and TSP-1-deficient mice (B, D). A) Slit lamp image of WT mouse cornea showing haze present within the circle of arrows, indicating original wound area. (B) Slit lamp image of TSP-1-deficient mouse cornea demonstrating lack of haze formation within original wound area (arrows). C) Whole mount immunolocalization of α-smooth muscle actin (SMA) within the stroma at the original wound site in WT mice. (D) TSP-1-deficient cornea demonstrating dramatic decrease in SMA. TOPRO3 was used as a counterstain to mark all cell nuclei. Bar = 50 μm.