Predicted effect-site concentrations of anaesthetics after intramuscular midazolam 0.02 mg/kg or dexmedetomidine 1 μg·kg−1. (A) propofol, (B) remifentanil. Time point 1 represents at induction, 2 at start of surgery, 3 at completion of surgery, 4 at eye opening, and 5 at extubation. TCI = target-controlled infusion. The bar represents mean (SD). * P=0.021; ** P=0.016.