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Two-dimensional differential gel electrophoresis (2D-DIGE) image of mice glomeruli. Prohibitin and annexin A2 were up-regulated in glomeruli of 20-week spontaneous type-2 diabetic KKAy mice, with a differential expression rate of 1.32 and 1.36, respectively. The 3-dimensional images indicated by arrows were generated by DeCyder™ 2-D Differential Analysis software. K20 represents 20-week-old KKAy mice; C20 represents 20-week-old C57BL/6 mice.
