Table 3.
Down-regulated glomerular proteins in KKAy mice.
| Spot ID | MW(Da) | pI | Protein name | Acc.no. SwissProt | Ratio (K20/C20) | Protein Score | Molecular function |
|---|---|---|---|---|---|---|---|
| 1338 | 52991 | 6.52 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial | Q91WD5 | −1.37 | 97 | Oxidoreductase |
| 1677 | 35720 | 5.3 | Aspartoacylase-2 | Q91XE4 | −1.29 | 88 | Hydrolase |
“K20/C20” represents 20-week-old spontaneous type-2 diabetic KKAy mice vs. 20-week-old C57BL/6 mice. Protein score is −10*Log(P), where P is the probability that the observed match is a random event. Protein scores greater than 55 are significant (P<0.05).