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. 2014 Dec 29;9(12):e115676. doi: 10.1371/journal.pone.0115676

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© 2014 Mariman et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) LPS-induced genes, significantly suppressed by VSL#3, were analyzed by using Metacore Network analysis (Transcription factor). STAT-1 was predicted to be a key driver of this cluster. DC were stimulated for 3 hours, and phosphorylation of NF-κBp65 (B) and STAT-1 (C) was quantified in nuclear extracts using the Trans-am assay. Absorbance values (mean ± SD) of 5 individual donors are shown. Rank-Wilcoxon paired test: * p<0.05, ** p<0.01.