TABLE 3.
Distribution of vacA and cagA allelic types according to histopathological findings in the antra of 276 dyspeptic patients
| Histopathological findingsb | No. (%) with vacA and cagA results
|
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
s1/m1
|
s1/m2
|
s2/m1
|
s2/m2
|
Mixed
|
Inca
|
Negative
|
||||||||
| cagA+ | cagA | cagA+ | cagA | cagA+ | cagA | cagA+ | cagA | cagA+ | cagA | cagA+ | cagA | cagA+ | cagA | |
| Nonatrophic gastritis | ||||||||||||||
| CG (n = 48) | 9 (19) | 2 (4) | 4 (8) | 6 (13) | 0 | 0 | 1 (2) | 0 | 4 (8) | 0 | 3 (6) | 0 | 1 (2) | 18 (38) |
| CAG (n = 185) | 80 (43) | 2 (1) | 36 (20) | 4 (2) | 2 (1) | 0 | 10 (6) | 10 (6) | 6 (3) | 4 (2) | 6 (3) | 4 (3) | 2 (1) | 19 (10) |
| Atrophic gastrits | ||||||||||||||
| CAAG (n = 24) | 9 (38) | 1 (4) | 10 (42) | 2 (8) | 0 | 0 | 0 | 0 | 1 (4) | 0 | 0 | 0 | 0 | 1 (4) |
| CAAGI (n = 17) | 9 (53) | 0 | 3 (18) | 0 | 0 | 0 | 0 | 0 | 1 (6) | 0 | 1 (6) | 0 | 0 | 3 (18) |
| Malignant lesions | ||||||||||||||
| Adenocarcinoma (n = 1) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 (100) | 0 | 0 | 0 | 0 | 0 |
| MALT lymphoma (n = 1) | 1 (100) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Total (n = 276) | 108 (39) | 5 (2) | 53 (19) | 12 (4) | 2 (1) | 0 | 11 (4) | 10 (4) | 13 (5) | 4 (1) | 10 (4) | 4 (1.4) | 3 (1) | 41 (15) |
a
vacA gene was incomplete (Inc) to yield a detectable PCR product for the vacA s or m region.
b
Abbreviations: CG, chronic gastritis; CAG, chronic active gastritis; CAAG, chronic active atrophic gastritis; CAAGI, chronic active atrophic gastritis with intestinal metaplasia; MALT, mucosa-associated lymphatic tissue.