Figure 1. Set-up of the filtration unit employed in the experiments.

The bulk was fed using a Tandem 1082 Pump and the retentate recirculated to the feed tank. the pressure was monitored by in-line transducers at the inlet, retentate outlet, and permeate outlet. was kept constant at 1–1.2 bar by a flow restriction valve. TRIS saline buffer at pH 8 was used as diafiltration buffer.