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. Author manuscript; available in PMC: 2014 Dec 29.
Published in final edited form as: Nanomedicine (Lond). 2014 Jan 10;9(11):1595–1612. doi: 10.2217/nnm.13.136

Figure 7. Results of uptake mechanism studies.

Figure 7

Effects of inhibitors on uptake of fluorescein isothiocyanate-labeled nanoparticles on (A) the VK2/E6E7 cell line and (B) the End1/E6E7 cell line. Cells are incubated with nanoparticles for 24 h and lysed by 1% Triton™ X-100 (Sigma-Aldrich, MO, USA). Nanoparticles are prepared with a concentration of chitosan–thioglycolic acid conjugate (w/v%) of 1, a sodium tripolyphosphate/chitosan–thioglycolic acid conjugate weight ratio of 0.96 and a drug/chitosan–thioglycolic acid conjugate weight ratio of −1. Data are shown as the mean ± the standard error of the mean (n = 3).

*p < 0.05 verus control.

**p < 0.01 versus control.

PMA: Phorbolmyristate acetate.