Figure 1. Pattern of iRhom2 expression in mice.
(A) Real-time PCR analysis of iRhom2 expression in 2-month-old mice. (B) Real-time PCR analysis of iRhom2 expression during development in the mouse dorsal skin. (C–E) Immunofluorescence staining of iRhom2, K14, AE15 and AE13 in the dorsal skin of wild-type mice at P9. (F) Real-time PCR analysis of iRhom2 mRNA expression in the epidermis and dermis of wild-type mice at P5. E: embryonic day; P: postnatal day. Green arrow in C indicates the ORS, green arrow in D indicates the IRS and medulla of the hair shaft, green arrow in E indicates the hair shaft cuticle and cortex keratins. White arrow in E indicates the dermal papilla. Scale bars: (C–E), 25 µm.