Table 2. Plasma troponin and creatine kinase measurements before and after occlusion of the LAD coronary artery.
Plasma Troponin | Creatine Kinase | ||||||
Time | pVEGF + GET (20 ms; 60 V) | pVEGF injection only | Sham | Time | pVEGF + GET (20 ms; 60 V) | pVEGF injection only | Sham |
Pre MI | 3.52±3.3 (ng/ml) | 1.8±1.7 (ng/ml) | 4.0±5.2 (ng/ml) | Pre MI | 409±289 (ng/ml) | 456±408 (ng/ml) | 696±206 (ng/ml) |
Post MI | 59±42 | 26±23 | 31±16 | Post MI | 2210±1604 | 2521±305 | 1363±348 |
1 hour | 31±35 | 9.6±11 | 21±8 | 1 hour | 3682±1968 | 4740±2338 | 2187±273 |
3 hours | 157±124 | 140±151 | 133±90 | 3 hours | 4488±2038 | 7289±3926 | 5246±1093 |
1 day | 6772±2396* | 3339±1295 | 3980±1600 | 1 day | 4361±122 | 9202±4610 | 6776±5143 |
2 days | 5789±2873# | 2144±347 | 2259±1232 | 2 days | 5072±4759 | 3235±1975 | 1498±1022 |
4 days | 1024±1117 | 369±53 | 554±37 | 4 days | 538±238 | 429±63 | |
14 days | 10.7±0 | 11.9±0 | 14 days | 420±106 | 1004±408 |
Enzyme values immediately after LAD occlusion was used as the baseline value. Data stated as mean ± SD.
*p<0.02 pVEGF+GET (20 milliseconds; 60 Volts) 1 day post operatively versus pVEGF injection only or Sham.
p<0.009 pVEGF+GET (20 milliseconds; 60 Volts) 2 days post operatively versus pVEGF injection only or Sham.