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. 2014 Dec 29;9(12):e116174. doi: 10.1371/journal.pone.0116174

Table 3. Plasma markers of hemostatic activity before and 5 min after lower body negative pressure (post-LBNP) was ceased because of presyncopal symptoms.

Baseline Post-LBNP P-value
PT (s) 10.7±0.5 10.5±0.3 0.163
aPTT (s) 27.7±2.0 27.1±1.8 0.081
vWF:Ag (IU l−1) 1016 [610–1371] 1292 [629–1743] 0.078
vWF:RCo (% d.N.) 115±46 128±47* 0.024
FVIII (IU l−1) 830±160 982±253* 0.011
TAT (µg l−1) 5.5±1.7 9.2±5.5 0.134
Protein C activity (% d.N.) 199±26 214±26* 0.007
t-PA (ng ml−1) 0.1±1.6 1.7±2.3* 0.017
D-dimer (mg l−1) 0.25 [0.17–0.51] 0.29 [0.19–0.56]* 0.031

Prothrombin time (PT), activated partial thromboplastin time (aPTT), von Willebrand factor antigen (vWF:Ag), von Willebrand factor ristocetin cofactor (vWF:RCo), coagulation factor VIII (FVIII), thrombin-antithrombin III complex (TAT), and tissue-type plasminogen activator (t-PA). Mean±SD and median [range], n = 7 (except for t-PA and D-dimer, n = 6), * significantly different from baseline, using the Benjamini-Hochberg procedure with a false discovery rate of 0.05.