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. 2014 Dec 29;9(12):e116117. doi: 10.1371/journal.pone.0116117

Table 1. Baseline characteristics.

Baseline characteristic Active UC (n = 10) Inactive UC (n = 7) Active CDc (n = 5) IC (n = 5) Controls (n = 10) p-value
Male/female (%) 6/4 (60.0/40.0) 4/3 (57.1/42.9) 2/3 (40.0/60.0) 1/4 (20.0/80.0) 5/5 (50.0/50.0) 0.64
Median (IQR) age (years) 55.0 (45.3–61.3) 51.1 (36.1–60.4) 45.9 (36.1–60.1) 69.1 (68.2–78.4) 57.7 (51.9–62.6) 0.35
Median (IQR) BMI 27.3 (23.1–29.7) 26.0 (22.7–26.5) 27.1 (20.2–30.4) 21.5 (19.7–22.1) 26.3 (22.4–29.4) 0.46
Median (IQR) duration of disease (years) 7.1 (0.6–20.1) 6.6 (4.0–14.4) 9.8 (7.6–15.0) NA NA 0.94
Extent of disease
left-sided colitis (%) 9 (90.0) 6 (85.7) NA NA NA 1
pancolitis (%) 1 (10.0) 1 (14.3) NA NA NA 1
colitis (%) NA NA 4 (80.0) NA NA NA
ileo-colitis (%) NA NA 1 (20.0) NA NA NA
Median (IQR) C-reactive protein (mg/dL) 4.1 (2.6–16.2) 1.6 (0.6–2.9) 2.9 (1.5–5.7) 6.1 (5.5–13.2) NA 0.54
Concomitant medication
5-Aminosalicylates (%) 9 (90.0) 5 (71.4) 3 (60.0) NA NA 0.39
Corticosteroids (%) 4 (40.0) 0 (0.0) 2 (40.0) NA NA 0.15
Azathioprine (%) 0 (0.0) 1 (14.3) 0 (0) NA NA 0.30
Methotrexate (%) 0 (0.0) 0 (0.0) 1 (20.0) NA NA 0.17
Biologics (%) 1 (10.0) 0 (0.0) 0 (0) NA NA 0.53
Active smoking (%) 1 (10.0) 2 (42.9) 1 (20.0) 1 (20.0) NA 0.81
Average (SD) total Mayo score 8 (±1.5) 0 (±0.5) NA NA NA 0.001
Median (IQR) histological Geboes score 5.2 (4.1–5.3) 0.0 (0.0–0.1) NA NA NA <0.001

IQR: interquartile range; BMI: body mass index; SD: standard deviation.