FIG 4.

ELISA reactivity of sera from infected or noninfected CF patients with immobilized purified catalase A1 from S. boydii IHEM 15155. Sera were obtained from CF patients without clinical or biological signs of fungal infections and without any fungus recovered from sputum samples (group A) and with A. fumigatus the sole filamentous fungus recovered from sputum samples and with serum antibodies directed toward A. fumigatus but not S. boydii by routine procedures (group B: B1, patients without anti-A. fumigatus catalase antibodies; B2, patients with anti-A. fumigatus catalase antibodies) and CF patients colonized by species of the S. apiospermum complex and exhibiting serum antibodies directed toward S. boydii but not A. fumigatus (group C). The cutoff (dotted line) and median OD values (solid lines) are indicated.