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Candidate small molecules screened in triplicate for inhibition of PfENR at a final concentration of 50 μM. (A) A set of small molecules taken from the 120 small molecule library tested for inhibition of PfENR against a known inhibitor for ENR, triclosan (TCL, 1) and commercially available inhibitor of β-ketoacyl-acyl-carrier protein synthase, cerulenin (CR). (B) Analogues of compound 9 (F) were tested for inhibition of PfENR at a final concentration of 50 μM.
