Table 1.
Clinicopathologic features of the 71 patients with microsatellite instability-low (MSI-L) tumors
| Characteristic | No. of patients (%) |
|---|---|
| Age at diagnosis, years (range) | 53.25 (29–80) |
| Female | 33 (46.5) |
| Race/ethnicity | |
| White | 50 (70.4) |
| Black | 10 (14.1) |
| Hispanic | 9 (12.7) |
| Other | 2 (2.8) |
| Colorectal cancer site | |
| Right colon | 22 (31.0) |
| Left colon | 19 (26.8) |
| Rectum | 30 (42.3) |
| Synchronous CRC | 3 (4.2) |
| Tumor stage | |
| Tis/I | 8 (11.3) |
| II | 12 (16.9) |
| III | 19 (26.8) |
| IV | 32 (45.1) |
| Neoadjuvant treatment | 23 (32.4) |
| Tumor histology | |
| Poorly differentiated | 16 (22.5) |
| Mucinous | 8 (11.3) |
| Family history | |
| Revised Bethesda | 37 (52.1) |
| Amsterdam I | 2 (2.8) |
| FDR with CRC | 13 (18.3) |
| PREMM1,2,6 score >5% | 29 (40.8) |
| Genetic counseling | 55 (77.5) |
| Germline testing | 21 (29.6) |
CRC, colorectal cancer; FDR, first-degree relative.