TABLE 2.
MICs of β-lactams for S. enterica serotype Enteridis isolate 1 (ESBL), serotype Babelsberg isolate 10 (ESBL), serotype Babelsberg isolate 12 (ApR), their respectives DH5α E. coli transformants, and E. coli DH5α
β-Lactam(s)a | MIC (mg/liter) for:
|
||||||
---|---|---|---|---|---|---|---|
Enteritidis isolate 1 | E. coli Tf 1-1b | Babelsberg isolate 10 | E. coli Tf 10-1 | Babelsberg isolate 12 | E. coli Tf 12-1 | E. coli DH5α | |
Ampicillin | >256 | >256 | >256 | >256 | >256 | >256 | 2 |
Amoxicillin-CLA | 16 | 4 | 16 | 16 | 16 | 16 | 2 |
Ticarcillin | >256 | >256 | >256 | >256 | >256 | >256 | 2 |
Ticarcillin-CLA | >256 | 4 | >256 | 128 | 64 | 32 | 1 |
Piperacillin | >256 | 32 | >256 | >256 | >256 | 256 | 0.5 |
Piperacillin-TZB | >256 | 0.5 | >256 | 64 | 4 | 1 | 0.5 |
Cefoxitin | 2 | 2 | 2 | 2 | 2 | 2 | 2 |
Ceftazidime | >256 | 16 | >256 | >256 | 0.5 | 0.125 | 0.125 |
Ceftazidime-CLA | 0.5 | 0.125 | 0.25 | 0.125 | NT | NT | NT |
Ceftriaxone | 32 | 1 | 32 | 8 | 0.06 | 0.03 | 0.03 |
Cefotaxime-CLA | 0.125 | 0.03 | 0.06 | 0.03 | NT | NT | NT |
Cefepime | 4 | 0.25 | 4 | 2 | 0.125 | 0.06 | 0.03 |
Aztreonam | 256 | 8 | >256 | >256 | 0.06 | 0.03 | 0.03 |
Imipenem | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 |
Abbreviations: CLA, clavulanic acid; TZB, tazobactam.
Tf, transformant.
NT, not tested.