Table 1.
Baseline demographics and characteristics of the study participants (M±SD or %)
Total sample
|
Baclofen group
|
Placebo group
|
||||
---|---|---|---|---|---|---|
n=30 | n=18 | n=15 | n=9 | n=15 | n=9 | |
Age (years) | 46.3±8.6 | 47.9±9.9 | 44.7±7.0 | |||
Male gender | 70 | 67 | 73 | |||
Hispanic ethnicity | 3 | 7 | 0 | |||
Racea | ||||||
American Indian | 7 | 13 | 0 | |||
Asian | 3 | 0 | 7 | |||
Caucasian | 43 | 20 | 67 | |||
African-American | 33 | 40 | 27 | |||
Multiracial or others | 13 | 27 | 0 | |||
Heavy drinking days (HDD) | 74.3±26.8 | 78.0±27.3 | 70.5±26.7 | |||
Cigarettes per day (CPD) | 24.7±9.4 | 24.9±10.2 | 24.4±8.9 | |||
Alcohol dependence scale (ADS) score | 14.7±7.9 | 15.8±8.4 | 13.5±7.5 | |||
Fagerström test for nicotine dependence (FTND) score | 7.2±1.8 | 7.1±1.6 | 7.3±2.1 | |||
Smoking contemplation ladder score | 5.3±1.4 | 5.3±1.8 | 5.3±1.0 | |||
Cue-reactivity experiment substudy | ||||||
Age (Years) | 45.2±9.3 | 45.0±11.6 | 45.3±6.9 | |||
Male Gender | 67 | 67 | 67 | |||
Hispanic Ethnicity | 6 | 11 | 0 | |||
Race | ||||||
American Indian | 6 | 11 | 0 | |||
Caucasian | 44 | 22 | 67 | |||
African-American | 33 | 33 | 33 | |||
Multiracial or others | 17 | 33 | 0 | |||
Heavy drinking days (HDD) | 73.8±26.8 | 74.3±30.6 | 73.2±24.2 | |||
Cigarettes per day (CPD) | 24.7±8.8 | 24.6±8.9 | 24.7±9.2 | |||
Alcohol dependence scale (ADS) score | 16.6±8.4 | 17.4±9.3 | 15.8±7.9 | |||
Fagerström test for nicotine dependence (FTND) score | 7.2±2.1 | 7.4±1.8 | 7.0±2.4 | |||
Smoking contemplation ladder score | 5.4±1.5 | 5.3±1.9 | 5.4±1.1 |
There were no differences in the baseline demographics and characteristics among groups, except for race (X2 (4, N=30)=11.2, p=0.025 and with race dichotomized: X2 (1, N=30)=6.7, p=0.01). This difference was not significant in the sample that participated in the cue-reactivity experiment substudy