TABLE 5.
Major Late CUS Findings and Neurodevelopmental Outcomes at 18 to 22 Months’ Corrected Age
| Late CUS | ||||
|---|---|---|---|---|
| Outcome at 18–22 mo Corrected Age | Normal, N = 321 | All Without Porencephalic Cyst, cPVL, Moderate to Severe VE, or Shunt, N = 419 | Porencephalic Cyst, cPVL, Moderate to Severe VE, or Shunt, n = 26 | Pa |
| Cognitive score, mean ± SD | 92.8 (13.2) | 92.4 (13.5) | 82.0 (18.2) | .0002 |
| Cognitive score <70 | 13/317 (4.1) | 20/415 (4.8) | 6/26 (23.1) | .0024 |
| Cognitive score <85 | 60/317 (18.9) | 84/415 (20.2) | 14/26 (53.9) | <.0001 |
| Any CP | 11/321 (3.4) | 17/419 (4.1) | 14/26 (53.9) | <.0001 |
| Moderate to severe CP | 1/321 (0.3) | 4/419 (1.0) | 9/26 (34.6) | <.0001 |
| NDI | 17/317 (5.4) | 25/415 (6.0) | 13/26 (50.0) | <.0001 |
| Significant gross motor impairment | 4/321 (1.3) | 7/419 (1.7) | 10/26 (38.5) | <.0001 |
| Unimpaired/mildly impaired | 220/317 (69.4) | 281/415 (67.7) | 7/26 (26.9) | <.0001 |
| NDI or death | 22/322 (6.8) | 38/428 (8.9) | 15/28 (53.6) | <.0001 |
Data presented as n/N (%) unless otherwise specified.
a
P values reflect comparisons between those with and without late CUS composite adverse finding (porencephalic cyst, cPVL, moderate to severe VE, or shunt).