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ACVR2B:Fc increases serum corticosterone in STZ-treated mice. Corticosterone concentration was significantly increased in STZ-ACVR2B:Fc mice compared to either Control or STZ-PBS by one-way ANOVA. See also Figure S2 for replication. Data shown are from Group B mice. Serum was collected 42 days after the start of ACVR2B:Fc or PBS injections in STZ-treated mice. Control, n = 4; STZ-PBS, n = 8; STZ-ACVR2B:Fc, n = 8.
