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Correlation analysis of test compounds evaluated for in vitro potency (IC50 values in HEK-AaDOP2 cells) and in vivo toxicity (percent mortality of A. aegypti L3-stage larvae following 24-hour treatment). The in vitro potency values for compounds that provided less than 10% inhibition of dopamine-stimulated cAMP in HEK-AaDOP2 cells were set to 20 µM.
