Fig. 2.

Effect of SEW2871 and JTE-013 on renal peritubular capillary perfusion at 6 hours after CLP. At 6 hours after CLP, there were significant decreases in the percentage of cortical peritubular capillaries with continuous flow and increases in the percentage with intermittent and no flow. Neither SEW2871 (10 mg/kg) nor JTE-013 (1 mg/kg), administered at the time of CLP, altered the distribution of capillaries with continuous or no flow. Data are mean ± S.E.M.; *P < 0.05 compared with the sham group; n = 7 in sham, n = 9 in CLP + vehicle, n = 5 in CLP + SEW2871, and n = 5 in CLP + JTE-013.