Table 4.
Inhibition of human LDL oxidation in vitro in relation to the concentration of the test compounds.
| Compound | % Inhibition (Relative to the Control) | |||||||
|---|---|---|---|---|---|---|---|---|
| Cu2+-Induction | AAPH Derived Peroxyl Radical–Induction | |||||||
| Concentration (µmol·L−1) | Concentration (µmol·L−1) | |||||||
| 1 | 10 | 100 | 500 | 1 | 10 | 100 | 500 | |
| Q3G | 7 ± 4.5c | 20 ± 9.2bc | 20 ± 1.8bc | 33 ± 8.6ab | 10 ± 2.6C | 10 ± 2.7C | 16 ± 7.2C | 29 ± 2.0C |
| Q3G stearate | 4 ± 9.4c | 14 ± 7.5bc | 21 ± 8.6bc | 29 ± 4.2b | 4 ± 5.9C | 11 ± 5.0C | 14 ± 7.5C | 27 ± 8.5C |
| Q3G oleate | 8 ± 7.4c | 18 ± 5.8bc | 14 ± 5.3bc | 28 ± 2.8bc | 12 ± 7.2C | 9 ± 2.8C | 15 ± 3.9C | 17 ± 13.6C |
| Q3G linoleate | 14 ± 3.4bc | 27 ± 7.8bc | 29 ± 5.9b | 34 ± 6.3ab | 5 ± 4.7C | 15 ± 7.8C | 23 ± 5.6C | 25 ± 5.4C |
| Q3G α-linolenate | 40 ± 5.6ab | 34 ± 5.1ab | 31 ± 2.9ab | 31 ± 3.5ab | 28 ± 9.5AB | 23 ± 4.3AB | 23 ± 2.0AB | 34 ± 6.3AB |
| Q3G eicosapentaenoate | 20 ± 8.8bc | 43 ± 6.8ab | 45 ± 3.1ab | 51 ± 2.6a | 21 ± 3.8A | 36 ± 6.7A | 38 ± 1.7A | 41 ± 2.9A |
| Q3G docosahexaenoate | 7 ± 5.5c | 14 ± 7.9bc | 27 ± 6.7bc | 43 ± 1.4ab | 13 ± 3.7BC | 9 ± 8.1BC | 30 ± 10.0BC | 27 ± 8.1BC |
Data from Cu2+- and peroxyl radical-induced LDL oxidation were statistically analyzed separately and presented as means ± standard deviation. Different letters (a,b,c… and A,B,C…) denote significant differences among test compounds and concentrations, for % inhibition of Cu2+- and peroxy radical- induced oxidation, respectively (p ≤ 0.05).