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Effect of KPFE (a) and KPFV (b) on the acetic acid-induced abdominal writhing test. KPFE, KPFV, or indomethacin (Indo) was subcutaneously administrated 30 min before acetic acid injection (1.2%, 0.1 mL/10 g). The number of acetic acid-induced abdominal writhings was counted for the following 30 min. * P < 0.05, ** P < 0.01, and *** P < 0.001 significantly different from the vehicle-treated group. Values represent the mean ± SEM of 5-6 mice.
