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C40-tPEG-Ex4-Cys (PEG-Ex4) promotes tube formation and activates Akt and vascular endothelial growth factor (VEGF) in the infarct border zone. A, Tube formation assay of human umbilical vein endothelial cells (HUVEC). *P < 0.05 vs. vehicle; **P < 0.01 vs. vehicle. B-E, Western blot analysis of total and phosphorylated level of Akt and AMPK as well as VEGF within cardiac tissue in the border area. *P < 0.05 vs. MI.
