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. 2014 Dec;26(6):669–677. doi: 10.3978/j.issn.1000-9604.2014.12.04

Table 2. The relationships between KDR and NRP-1 CNG and clinical pathological parameters in non-small cell lung cancer.

Parameters N VEGFR2
χ2 P NRP1
χ2 P
Low High Low High
Gender 1.64 0.2 0.44 0.51
   Male 27 20 7 18 9
   Female 13 7 6 10 3
Age 1.09 0.3 0.01 0.94
   ≤60 years 23 14 9 16 7
   >60 years 17 13 4 12 5
Pathological type 1.03 0.31 1.91 0.17
   Squamous 20 12 8 12 8
   Adenocarcinoma 20 15 5 16 4
Clinical stage 10 0.02 12.47 0.01
   Phase I 6 5 1 5 1
   Phase II 5 4 1 4 1
   Phase III 15 13 2 14 1
   Phase IV 14 5 9 5 9
Differentiation 9.12 0.01 7.22 0.03
   Low 12 4 8 5 7
   Medium 17 14 3 13 4
   High 11 9 2 10 1
Lymph node metastasis 5.79 0.02 4.68 0.03
   (+) 23 12 11 13 10
   (−) 17 15 2 15 2

KDR, kinase insert domain receptor; NRP-1, neuropilin-1; CNG, copy number gain; VEGFR2, vascular endothelial growth factor receptor 2.