Table 2. The relationships between KDR and NRP-1 CNG and clinical pathological parameters in non-small cell lung cancer.
| Parameters | N | VEGFR2 | 
χ2 | P | NRP1 | 
χ2 | P | ||
|---|---|---|---|---|---|---|---|---|---|
| Low | High | Low | High | ||||||
| Gender | 1.64 | 0.2 | 0.44 | 0.51 | |||||
| Male | 27 | 20 | 7 | 18 | 9 | ||||
| Female | 13 | 7 | 6 | 10 | 3 | ||||
| Age | 1.09 | 0.3 | 0.01 | 0.94 | |||||
| ≤60 years | 23 | 14 | 9 | 16 | 7 | ||||
| >60 years | 17 | 13 | 4 | 12 | 5 | ||||
| Pathological type | 1.03 | 0.31 | 1.91 | 0.17 | |||||
| Squamous | 20 | 12 | 8 | 12 | 8 | ||||
| Adenocarcinoma | 20 | 15 | 5 | 16 | 4 | ||||
| Clinical stage | 10 | 0.02 | 12.47 | 0.01 | |||||
| Phase I | 6 | 5 | 1 | 5 | 1 | ||||
| Phase II | 5 | 4 | 1 | 4 | 1 | ||||
| Phase III | 15 | 13 | 2 | 14 | 1 | ||||
| Phase IV | 14 | 5 | 9 | 5 | 9 | ||||
| Differentiation | 9.12 | 0.01 | 7.22 | 0.03 | |||||
| Low | 12 | 4 | 8 | 5 | 7 | ||||
| Medium | 17 | 14 | 3 | 13 | 4 | ||||
| High | 11 | 9 | 2 | 10 | 1 | ||||
| Lymph node metastasis | 5.79 | 0.02 | 4.68 | 0.03 | |||||
| (+) | 23 | 12 | 11 | 13 | 10 | ||||
| (−) | 17 | 15 | 2 | 15 | 2 | ||||
KDR, kinase insert domain receptor; NRP-1, neuropilin-1; CNG, copy number gain; VEGFR2, vascular endothelial growth factor receptor 2.