Table 1.
Correlation of Rab27b expression with clinicopathological characteristics of 113 CRC patients.
| Groups | Number | Rab27b | χ 2 | P value | |
|---|---|---|---|---|---|
| + | % | ||||
| Gender | |||||
| Male | 73 | 36 | 49.3 | 2.98 | 0.085 |
| Female | 40 | 13 | 32.5 | ||
| Age (years) | |||||
| ≥60 | 75 | 35 | 46.7 | 0.99 | 0.319 |
| <60 | 38 | 14 | 36.8 | ||
| Tumor size (cm) | |||||
| ≥5 | 47 | 24 | 51.1 | 2.33 | 0.127 |
| <5 | 63 | 23 | 36.5 | ||
| Insufficient data | 3 | 2 | |||
| Tumor location | |||||
| Colon | 57 | 30 | 52.6 | 4.16 | 0.125 |
| Rectum | 52 | 18 | 34.6 | ||
| Ileocecal junction | 4 | 1 | 25.0 | ||
| Histological type | |||||
| Adenocarcinoma | 103 | 43 | 41.7 | 1.24 | 0.266 |
| Nonadenocarcinoma | 10 | 6 | 60.0 | ||
| Tumor differentiation | |||||
| Well | 1 | 0 | 0.0 | 0.98 | 0.613 |
| Moderate | 93 | 41 | 44.1 | ||
| Poor | 14 | 7 | 50.0 | ||
| Insufficient data | 5 | 1 | |||
| Serum CEA level (ng/mL) | |||||
| ≥15 | 12 | 9 | 75.0 | 8.31 | 0.004* |
| <15 | 73 | 23 | 31.5 | ||
| Insufficient data | 28 | 17 | |||
| Lymph node metastasis | |||||
| Positive | 44 | 28 | 63.6 | 12.06 | 0.001* |
| Negative | 69 | 21 | 30.4 | ||
| Distant metastasis | |||||
| Positive | 5 | 5 | 100.0 | 6.83 | 0.009* |
| Negative | 108 | 44 | 40.7 | ||
| TNM stage | |||||
| Stages I, II | 65 | 19 | 29.2 | 12.44 | 0.001* |
| Stages III, IV | 48 | 30 | 62.5 | ||
* P < 0.05.