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. 2014 Oct 4;5(21):10803–10815. doi: 10.18632/oncotarget.2506

Table 3. Stratification analysis of Oct-4 and Nanog expression in 126 breast cancer samples.

Factors N Oct+ Nan+ Nan/Oct+ Nan/Oct P1 P2 P3
Age
 < 35 Y 18 4 8 2 8 0.062 0.499 0.281
 > 35 Y 108 48 39 24 45
Tumor size 24 8 2 0 14 0.562 0.005 0.016
 T1
 T2 83 37 36 20 30
 T3 19 7 9 6 9
Histological grade
 I 15 1 2 0 12 0.001 0.001 0.001
 II 57 12 10 4 39
 III 54 39 35 22 2
Clinical stage
 DCIS 16 9 8 1 0 0.151 0.280 0.189
 IDC 110 43 39 25 53
Lymph node metastasis
 pN0 50 12 9 2 31 0.006 0.001 0.001
 pN1 44 20 15 6 15
 pN2 27 17 19 15 6
 pN3 5 3 4 3 1
Molecular type
 Luminal A 69 20 20 6 35 0.001 0.005 0.001
 Luminal B 12 4 4 1 5
 Basal-like 19 15 14 12 2
 Her-2+ 26 13 9 7 11

DCIS, ductal carcinoma in situ; IDC, Invasive ductal carcinoma; P1: Oct-4; P2: Nanog; P3: Oct-4+/Nanog+.