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. 2014 Oct 11;5(21):10886–10900. doi: 10.18632/oncotarget.2540

Figure 8. Prognostic significance of ITCH expression in different breast cancer subtypes.

Figure 8

(A) IHC scoring of ITCH protein in different breast cancer cases. The staining scores were as follows; 0= no staining, 1= weak staining, 2= moderate staining, 3= strong staining, 4= very strong staining. (B) IHC scoring of YAP protein in different breast cancer cases. The staining scores were as follows; 0= no staining, 1= weak staining, 2= moderate staining, 3= strong staining. C-E. Kaplan-Meier survival curves obtained from Kaplan-Meier Plotter recourse showing the correlation between ITCH mRNA expression and relapse-free survival (RFS), overall survival (OS), distant metastasis-free survival (DMFS), and post-progression survival (PPS) in breast cancer cohort (C); RFS in lymph node positive breast cancer samples (D); RFS and OS in Luminal A breast cancer patients (E).