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. 2014 Nov;5(11-12):436–444. doi: 10.18632/genesandcancer.38

Figure 1. Tumor suppressive effects of miR-31 in TE-7 ESCC cells.

Figure 1

(A) Cell viability was determined by MTT assay. Transfection of miR-31 inhibited cell viability of TE-7 cells. (B) miR-31 treatment inhibited colony formation capacity of TE-7 cells by about 43% as shown in the lower panel, a representative colony formation assay was shown (upper panel). (C) Invasive ability of TE-7 cells was inhibited over 90% by miR-31 treatment. Representative pictures of invaded cells (upper panels); cell number per 1 mm2 was counted under 100 X magnification and summarized (lower panel). (D) The effects of miR-31 on E2F2 and STK40 were shown by real time RT-PCR. Transfection of miR-31 can inhibit mRNA levels of E2F2 and STK40. The data were the average of three independent experiments and presented as means ± SEM. * indicating P < 0.05 con, control.