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. 2014 Nov;5(11-12):460–469. doi: 10.18632/genesandcancer.36

Figure 4. Influence of Caspase-inhibition on Taurolidine-inducedApoptosis Induction.

Figure 4

Neuroblastoma cells were treated with the indicated concentrations of TRD and 100 μM caspase inhibitors. The proportion of apoptotic cells was determined by flow cytometry and staining with Annexin V and PI 48 h after treatment initiation. Values represent the mean ± SD of three independent experiments, * (TRD 250 μM + NC vs. Z-IETD), † (TRD 250 μM + NC vs. Z-LEHD) and ‡ (TRD 250 μM + NC vs. Z-VAD); p ≤ 0.05. NC = Negative control.