Table 1. Demographics and outcomes.
N=377 | |
Age (years) | 33 (24-49) |
Male gender | 81% |
BMI (kg/m2) | 25.8 (22.9-30.1) |
Blunt injury rate | 61% |
ISS | 18 +/- 15 |
ED arrival GCS | 14 (7-15) |
AIS-head | 0 (0-4) |
Prehospital crystalloid (mL) | 100 (0-250) |
ED admit temperature (°) | 36.2 +/- 0.9 |
Admit pH | 7.31 +/- 0.12 |
Admit base excess | -3 +/- 6 |
Admit INR | 1.1 (1-1.2) |
Admit PTT (s) | 28 (26-31) |
Admit platelet count (x 109/L) | 274 (225-332) |
Admit fibrinogen (mg/dL) | 228 +/- 96 |
Admit Factor II (% activity) | 75 +/- 21 |
Admit Factor V (% activity) | 40 (24-57) |
Admit Factor VII (% activity) | 82 (62-107) |
Admit Factor VIII (% activity) | 167 (85-266) |
Admit Factor IX (% activity) | 123 +/- 44 |
Admit Factor × (% activity) | 78 +/- 22 |
Admit ATIII (% activity) | 74 +/- 27 |
Admit protein C (% activity) | 82 +/- 28 |
Admit D-dimer (ug/mL) | 3.34 (0.58-6.77) |
Admit CK R-time (min) | 4.6 +/- 1.4 |
Admit CK K-time (min) | 1.3 (1.2-1.7) |
Admit CK alpha angle (°) | 69.3 +/- 6.1 |
Admit CK MA (mm) | 64.4 +/- 5.8 |
Admit CK LY30 (%) | 0.8 (0.1-2.7) |
Admit FLEV (mg/dL) | 368 +/- 90 |
pRBC 0-24 hours (units) | 0 (0-3) |
FFP 0-24 hours (units) | 0 (0-2) |
PLTS 0-24 hours (units) | 0 (0-0) |
MT in 24 hours | 14% |
Total hospital days | 6 (3-17) |
Ventilator free days | 2 (0-6) |
VAP rate | 1% |
ARDS rate | 11% |
MOF rate | 9% |
Mortality rate at 6 hours | 1% |
Mortality rate at 24 hours | 3% |
Mortality rate at discharge | 12% |
TE complication rate | 6% |
Patient demographics for the 377 patients. Data are mean +/- SD, median (inter-quartile range), or n (%) as indicated. Data for skewed variables reported as median with inter-quartile ranges. BMI=body mass index. ED=emergency department. GCS=Glascow Coma Scale. ISS=injury severity score. AIS=abbreviated injury score. INR=international normalized ratio. PTT=partial thromboplastic time. ATIII=antithrombin III. CK=citrated kaolin. R-time=reaction time. MA=maximum amplitude. LY30=lysis at 30 min. FLEV=functional fibrinogen level. pRBC=packed red blood cell units. FFP=fresh frozen plasma units. PLTS=platelet units. MT=massive transfusion. Ventilator free days, counted for the first 28 days of hospitalization. Patients who expired received 0 ventilator free days. VAP=ventilator associated pneumonia. ARDS=acute respiratory distress syndrome by Berlin criteria. MOF=multiple organ failure. TE=thromboembolic