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. 2014 Dec 10;9:183. doi: 10.1186/s13023-014-0183-8

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© Desplantes et al.; licensee BioMed Central. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Bone marrow morphology in patients with G6PC3 congenital neutropenia. (A) Typical global bone marrow morphology: rich cellularity with predominant granulopoiesis (G), some erythroblasts (E), and one micromegakaryocyte (MK). (B) Predominant granulopoiesis with some myelocytes (M), very few metamyelocytes (MN), and a high number of mature neutrophils (N). (C) Details of neutrophils: hypersegmented appearance with thin opening between lobes and chromatin clumps. (D) Examples of micromegakaryocytes.