Table 2.

Pooled analysis of studies exploring the role of TLR4 Asp299Gly in UC

Study	Cases (Events/Total)	Controls (Events/Total)	Odds ratio	95% CI	P value
Arnott et al. 2004 [ 31 ]	35/492	33/378	0,801	0,49 to 1,31
Franchimont et al. (1) 2004 [ 32 ]	32/326	14/278	2,052	1,07 to 3,93
Torok et al. 2004 [ 33 ]	18/196	12/290	2,343	1,10 to 4,98
Braat et al. 2005 [ 34 ]	24/452	13/274	1,126	0,56 to 2,25
Gazouli et al. 2005 [ 36 ]	6/170	6/200	1,183	0,37 to 3,73
Oostenbrug et al. 2005 [ 37 ]	21/358	27/592	1,304	0,72 to 2,34
Baumgart et al. 2007 [ 21 ] (1)	8/236	16/404	0,851	0,36 to 2,02
Baumgart et al. 2007 [ 21 ] (2)	24/290	49/806	1,394	0,84 to 2,31
Browning et al. 2007 [ 42 ]	51/810	44/832	1,203	0,79 to 1,82
Riis et al. 2007 [ 43 ]	53/808	152/1236	0,501	0,36 to 0,69
De Ridder et al. 2007 [ 23 ] (1)	33/452	20/488	1,843	1,04 to 3,26
De Ridder et al. 2007 [ 23 ] (2)	4/62	20/488	1,614	0,53 to 4,88
Rigoli et al. 2008 [ 45 ]	3/90	8/206	0,853	0,22 to 3,29
Manolakis et al. 2013 [ 46 ]	41/374	33/548	1,921	1,19 to 3,10
Current study 2014	6/68	10/224	2,071	0,72 to 5,92
Total (fixed effects)	359/5184	457/7244	1,092	0,94 to 1,26	0.20
Total (random effects)	359/5184	457/7244	1,268	0,95 to 1,69