Table 4.
Effect of CP and NaHS on kidney and tubular functions, (n = 10).
| Groups |
Creatinine clearance
(mL min -1 ) |
creatinine clearance
(mL min -1 per gram of kidney tissue) |
Fractional excretion of sodium |
Fractional excretion
of potassium |
|---|---|---|---|---|
| Controls | 0.89 ± 0.06 | 0.48 ± 0.03 | 0.86 ± 0.03 | 10.32 ± 0.30 |
| CP | 0.47 ± 0.06* | 0.25 ± 0.02* | 2.69 ± 0.20* | 23.92 ± 1.90* |
| CP + NaHS | 0.77 ± 0.05† | 0.43 ± 0.04† | 1.15 ± 0.09† | 12.56 ± 1.10† |
*
Values are significantly different compared to control group; p < 0.01) within the same column.
†
Values are significantly different compared to cisplatin group; p < 0.01) within the same column.