Table 3.
Longitudinal mixed-effects model for future eGFR using HtTKV as baseline predictor (class 1 and class 2 patients)
| Variable | Class 1 | Class 2 (A and B) | ||
|---|---|---|---|---|
| Estimate (95% CI) | P Value | Estimate (95% CI) | P Value | |
| Intercept | 35.87 (20.31 to 51.42) | <0.001 | 22.78 (−13.64 to 59.19) | 0.21 |
| Sex (reference is male) | −0.95 (−2.89 to 0.99) | 0.34 | −2.65 (−8.09 to 2.79) | 0.33 |
| Age at HtTKV0 (yr) | −0.18 (−0.28 to −0.08) | <0.001 | −0.07 (−0.35 to 0.20) | 0.59 |
| eGFR at HtTKV0 (ml/min per 1.73 m2) | 0.90 (0.85 to 0.94) | <0.001 | 0.86 (0.71 to 1.00) | <0.001 |
| Log2(HtTKV0) (ml/m) | −1.89 (−3.00 to −0.79) | <0.001 | −0.90 (−3.99 to 2.19) | 0.56 |
| Years from HtTKV0 | 7.65 (3.39 to 11.92) | <0.001 | −0.81 (−9.30 to 7.68) | 0.85 |
| Sex, years from HtTKV0 (interaction) | −0.35 (−0.85 to 0.16) | 0.18 | 0.21 (−0.99 to 1.41) | 0.73 |
| Age at TKV, years from HtTKV0 (interaction) | 0.03 (0.002 to 0.055) | 0.03 | 0.03 (−0.02 to 0.09) | 0.21 |
| eGFR at HtTKV, years from HtTKV0 (interaction) | −0.004 (−0.017 to 0.009) | 0.55 | 0.05 (0.02 to 0.08) | 0.004 |
| Log2(HtTKV), years from HtTKV0 (interaction) | −1.15 (−1.46 to −0.85) | <0.001 | −0.65 (−1.36 to 0.06) | 0.07 |