Table 5.
Longitudinal mixed-effects model for future eGFR using classification as baseline predictor (class 1 patients)
| Variable | Estimate (95% CI) | P Value |
|---|---|---|
| Intercept | 21.18 (9.75 to 32.61) | 0.003 |
| Sex (reference is male) | −1.26 (−3.65 to 1.12) | 0.30 |
| Age at HtTKV0 (yr) | −0.26 (−0.40 to −0.11) | <0.001 |
| eGFR at HtTKV0 (ml/min per 1.73 m2) | 0.90 (0.85 to 0.95) | <0.001 |
| Subclass 1Ba | 0.58 (−3.60 to 4.76) | 0.79 |
| Subclass 1Ca | −1.14 (−5.37 to 3.08) | 0.6 |
| Subclass 1Da | −1.93 (−6.63 to 2.76) | 0.42 |
| Subclass 1Ea | −6.26 (−11.91 to −0.62) | 0.03 |
| Years from HtTKV0 | −0.23 (−3.42 to 2.96) | 0.9 |
| Sex, years from HtTKV0 (interaction) | 0.19 (−0.42 to 0.81) | 0.54 |
| Age at HtTKV, years from HtTKV0 (interaction) | −0.02 (−0.06 to 0.02) | 0.32 |
| eGFR at HtTKV, years from HtTKV0 (interaction) | 0.00 (−0.02 to 0.01) | 0.9 |
| Subclass 1B,a years from HtTKV0 (interaction) | −1.33 (−2.44 to −0.23) | 0.02 |
| Subclass 1C,a years from HtTKV0 (interaction) | −2.63 (−3.74 to −1.51) | <0.001 |
| Subclass 1D,a years from HtTKV0 (interaction) | −3.48 (−4.73 to −2.23) | <0.001 |
| Subclass 1E,a years from HtTKV0 (interaction) | −4.78 (−6.35 to −3.20) | <0.001 |
a
Reference is subclass 1A. Patients were subclassified based on HtTKV ellipsoid.