Table 2.

Hematological findings (I)

Male, female, week 13
Sex	Dose (mg/kg)		WBC (103/μL)	RBC (106/μL)	Hb (g/dL)	HCT (%)	MCV (fL)	MCH (Pg)	MCHC (g/dL)	RETI (109 cells/L)	RETI (%)	PLT (103/μL)	PT (sec)	APTT (sec)
Male	GI(0)	Mean	5.28	8.25	14.3	43.4	52.6	17.3	32.9	139.9	1.69	1021	11.7	19.9
		SD	1.83	0.30	0.4	1.2	1.4	0.6	0.6	36.1	0.43	122	1.7	1.9
		N	10	10	10	10	10	10	10	10	10	10	10	10
	G2 (500)	Mean	5.13	8.23	14.4	43.6	53.1	17.5	32.9	150.6	1.83	974	11.6	19.9
		SD	1.40	0.34	0.4	1.0	1.9	0.8	0.5	25.0	0.28	85	1.2	0.8
		N	10	10	10	10	10	10	10	10	10	10	10	10
	G3 (1,000)	Mean	4.66	8.38	14.7	44.4	53.0	17.5	33.0	145.7	1.74	977	10.3	19.6
		SD	1.29	0.38	0.4	1.2	1.6	0.6	0.4	18.7	0.22	110	0.9	1.5
		N	10	10	10	10	10	10	10	10	10	10	10	10
	G4 (2,000)	Mean	5.07	8.32	14.6	44.4	53.3	17.5	32.9	143.5	1.73	973	11.6	20.3
		SD	1.23	0.34	0.6	1.8	0.9	0.4	0.4	18.5	0.23	96	2.0	1.4
		N	10	10	10	10	10	10	10	10	10	10	10	10
Female	Gl(0)	Mean	3.26	7.64	14.2	43.0	56.4	18.6	33.0	170.9	2.26	1171	8.5	15.6
		SD	0.77	0.34	0.6	1.4	1.4	0.5	0.4	37.0	0.57	306	0.6	0.7
		N	10	10	10	10	10	10	10	10	10	10	10	10
	G2 (500)	Mean	3.71	7.39	14.0	42.2	57.2	19.0	33.2	178.3	2.44	1204	8.3	15.9
		SD	1.78	0.40	0.5	1.4	2.0	0.8	0.5	71.9	1.05	172	0.3	0.9
		N	10	10	10	10	10	10	10	10	10	10	10	10
	G3 (1,000)	Mean	3.12	7.35	14.1	42.7	58.2	19.2	33.0	163.3	2.23	1139	8.3	15.3
		SD	1.31	0.29	0.4	1.6	3.5	0.9	0.5	27.3	0.41	115	0.5	1.0
		N	10	10	10	10	10	10	10	10	10	10	10	10
	G4 (2,000)	Mean	3.51	7.53	14.2	43.0	57.2	18.9	33.0	169.0	2.27	1122	8.7	15.1
		SD	1.51	0.45	0.6	1.6	2.4	0.7	0.4	46.5	0.68	108	0.7	0.7
		N	10	10	10	10	10	10	10	10	10	10	10	10

Abbreviations: WBC, white blood cell count; RBC, red blood cell count; Hb, hemoglobin; HCT, hematocrit; MCV, mean cell volume; MCH, mean corpuscular hemoglobin; MCHC, mean cell hemoglobin concentration; RETI, reticulocyte ratio; PLT, platelet count; PT, prothrombin time; APTT, activated partial thromboplastin time; G, group; SD, standard deviation (not significantly different from control); sec, seconds.