Table 3.
NK cell activity in SiO2 NP-fed mice
| Effector/target ratio | NK cell activity (% mean ± SD)
|
||||
|---|---|---|---|---|---|
| NC | SiO2EN20(−) | SiO2EN100(−) | SiO2EN20(R) | SiO2EN100(R) | |
| 100:1 | 76.61±3.622 | 46.95±6.117* | 71.12±19.99 | 55.04±4.845** | 82.50±4.560 |
| 50:1 | 58.11±1.691 | 40.45±3.662 | 48.87±10.36 | 45.39±1.263 | 58.96±3.361 |
| 25:1 | 53.12±2.229 | 37.51±1.1160 | 42.91±2.325 | 46.07±0.842 | 54.71±2.899 |
Notes: Data are presented as the mean ± SD; n=5. Nonparametric Tukey’s multiple comparison test (*P<0.01; **P<0.001 versus NC).
Abbreviations: NK, natural killer; SiO2, silicon dioxide; NP, nanoparticle; SD, standard deviation; NC, normal control; SiO2EN(−), negatively charged silicon dioxide; SiO2EN(R), silicon dioxide modified with L-arginine; n, number.