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. Author manuscript; available in PMC: 2014 Dec 30.
Published in final edited form as: Bone Marrow Transplant. 2013 Jun 17;48(11):1437–1443. doi: 10.1038/bmt.2013.79

Table 2.

Toxicities

Toxicity assessmenta (n = 29)

Total toxicity (n = 29) Clofarabine to conditioning
(n = 29)
Conditioning to day + 12 (n = 29)



Grade 1–2 Grade 3–4 Grade 1–2 Grade 3–4 Grade 1–2 Grade 3–4
Renal (creatinine) 9 (31%) 1 (3%) 2 (7%) 0 9 (31%) 1 (3%)
Hepatic (total bilirubin) 14 (48%) 3 (10%) 12 (41%) 2 (7%) 8 (28%) 0
Hepatic (SGOT) 14 (48%) 9 (31%) 14 (48%) 7 (24%) 17 (59%) 3 (10%)
Cardiac 2 (7%) 0 0 0 2 (7%) 0
Skin 1 (3%) 0 1 (3%) 0 0 0
Infection 0 12 (41%)b 0 3 (10%) 0 10 (34%)b
a

All toxicities calculated by CTCAE v.3 grading criteria expressed as % of patients experiencing the maximum toxicity level achieved during the indicated time period.

b

Includes one grade 5 from sepsis on day − 1.