Table 4.
Risk factors for VAP occurrence before day 28 (univariate and multivariate analyses)
| Parameters | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI (HR) | P -value | HR | 95% CI (HR) | P -value | |
| Age | 0.97 | (0.95, 0.98) | <0.001 | 0.97 | (0.95, 0.98) | <0.001 |
| Gender (male) | 1.82 | (0.88, 3.78) | 0.110 | |||
| BMI | 0.99 | (0.93, 1.05) | 0.730 | |||
| Smoking | 1.89 | (1.09, 3.30) | 0.024 | 1.67 | (0.95, 2.93) | 0.078 |
| Alcohol intake | 0.85 | (0.35, 2.09) | 0.730 | |||
| Lung contusion | 2.41 | (1.37, 4.24) | 0.002 | |||
| GCS | 0.97 | (0.85, 1.12) | 0.710 | |||
| SAPS II | 0.98 | (0.95, 1.00) | 0.068 | 1.01 | (0.98, 1.04) | 0.590 |
| NMB agents | 2.11 | (0.97, 4.61) | 0.061 | |||
| Mannitol | 1.25 | (0.72, 2.17) | 0.430 | |||
| Thiopental | 1.36 | (0.78, 2.38) | 0.270 | 0.95 | (0.53, 1.69) | 0.950 |
| Fever control | 3.06 | (1.58, 5.94) | <0.001 | 2.73 | (1.38, 5.38) | 0.005 |
BMI: body mass index; GCS: Glasgow Coma Scale; NMB: neuromuscular blocker; SAPS II: Simplified Acute Physiology Score II; VAP: ventilator-associated pneumonia.