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. 2014 Dec 14;2:173. doi: 10.1186/s40478-014-0173-z

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© Wakabayashi et al.; licensee BioMed Central. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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AMBRA1 immunoreactivity in anterior horn cells from normal and diseased controls and patients with ALS. The proportions of neurons showing intense/moderate (++, black column), weak (+, gray column), or no immunostaining for AMBRA1 (−, white column) relative to the total number of neurons in the anterior horn are indicated.