Table 2.
Genotypes and alleles frequency of PON1 Q192R and L55M polymorphisms in patients and control groups
| Control N=50 | Patients N=134 | OR (95% CI) | P value | |
|---|---|---|---|---|
| Q192R | ||||
| 33 (66%) | 60 (44.8%) | Reference | 0.02 | |
| QR | 12 (24%) | 59 (44%) | 2.1 (1.2–4.8) | |
| RR | 5 (10%) | 15 (11.2%) | 3.2 (1.3–6.6) | |
| L55M | ||||
| LL | 7 (14%) | 23 (17.2%) | Reference | 0.009 |
| LM | 14 (28%) | 66 (49.3%) | 2.1 (1.4–5.5) | |
| MM | 29 (58%) | 45 (33.5%) | 2.8 (1.7-6.2) | |
| Allele | 2n=100 | 2n=268 | ||
| 192Q | 78 (78%) | 179 (66.8%) | Reference | 0.03 |
| 192R | 22 (22%) | 89 (33.2%) | 1.9 (1.2–3.2) | |
| 55 L | 28 (28%) | 112 (42%) | Reference | 0.01 |
| 55 M | 72 (72%) | 156 (58%) | 2.0 (1.1–3.5) | |