Table 3.
Genotypes and alleles frequency of PON1 Q192R and L55M polymorphisms in T2DM and T2DM+CVD patient groups
| T2DM N = 68 | T2DM+CVD N=66 | OR (95% CI) | P value | |
|---|---|---|---|---|
| Q192R | ||||
| 39 (57.4%) | 21 (32%) | Reference | 0.01 | |
| QR | 23 (33.8%) | 36 (54.4%) | 1.7 (1.0–3.8) | |
| RR | 6 (8.8%) | 9 (13.6%) | 2.1 (1.3–4.6) | |
| L55M | ||||
| LL | 11 (35%) | 12 (41%) | Reference | 0.9 |
| LM | 34 (47%) | 32 (45 %) | 1.08 (0.8–1.4) | |
| MM | 23 (18%) | 22 (14%) | 0.99 (0.7–1.2) | |
| Allele | 2n=136 | 2n=132 | ||
| 192Q | 101 (74%) | 78 (59%) | Reference | 0.008 |
| 192R | 35 (26%) | 54 (41%) | 1.3 (1.0–2.7) | |
| 55 L | 56 (59%) | 56 (64%) | Reference | 0.8 |
| 55 M | 80 (41%) | 76 (36%) | 0.9 (0.8–1.1) | |