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. 2014 Nov 16;2014:524517. doi: 10.1155/2014/524517

Figure 6.

Figure 6

Exogenous glucose infusion rates (GIR) and 2-deoxyglucose uptake into muscle. The GIR required to maintain the glucose levels at the clamp point (6-7 mmol/L) was higher (P < 0.01) in the D + E group rats than that in the D group rats, while it was still significantly lower (P < 0.01) than that in the C group rats. The GIR did not differ between the C group rats and in the C + E group rats (a). Exenatide treatment for 8 weeks markedly increased glucose uptake in diabetic rat gastrocnemius compared with the vehicle-treated diabetic rats (P < 0.01). Increased glucose uptake was also found in the C + E group rats compared with the C group rats, but this did not reach statistical significance (b). C: nondiabetic control; C + E: nondiabetic + exenatide; D: diabetic; D + E: diabetic + exenatide. Data are presented as mean ± SD. * P < 0.01, # P < 0.05 compared with basal. β P < 0.01, α P < 0.05 compared with C group. σ P < 0.01, γ P < 0.05 compared with C + E group. § P < 0.01,  φ P < 0.05 compared with D group.