Skip to main content
. Author manuscript; available in PMC: 2015 May 27.
Published in final edited form as: Nature. 2014 Nov 27;515(7528):577–581. doi: 10.1038/nature13988

Extended Data Figure 4. mLama4 and mAlg8 bind H-2Kb and stimulate CD8+ T cell lines generated against d42m1-T3 following αPD-1 immunotherapy.

Extended Data Figure 4

a, IFN-γ release by CTL 62, CTL 73, or CTL 74 T cell lines following stimulation with naïve irradiated splenocytes pulsed with WT or mutant forms of Lama4 or Alg8 peptides. b, RMA-S cells were incubated with 8 amino acid peptides of mLama4 or mAlg8 and surface expression of H-2Kb or H-2Db was assessed by flow cytometry. Mean fluorescent intensity of H-2Kb and H-2Db was expressed as peptide binding score. Data presented are representative of at least two independent experiments.